Coronavirus pandemic - how are you affected?

[Jagosaurus]

Small pox took about 200 years of refining (look up cow pox) and a 20 years of an active campaign to eradicate.

From what I've read, this could become seasonal and basically be the next flu we fight different variants of. That changes the discussion of eradication as well. This may be here to stay for some time.

I've had to be in front of clients since April of 2020 for my job (B2B IT is a DOD essential pillar), and also I've had a fairly rad case of COVID (highly likely contracted from a family member) ... so my view is 1st hand on both sides there. There's a risk of driving my truck to work everyday also. I take that risk, some don't. Life is full of risks. Be smart, be reasonable, and don't live in fear.

[RCBH928]

Sometimes I think maybe we should let people choose vaccine or not, and let natural selection just happen. They say every year many people die of the regular flue any ways.

Small pox took about 200 years of refining (look up cow pox) and a 20 years of an active campaign to eradicate.

From what I've read, this could become seasonal and basically be the next flu we fight different variants of. That changes the discussion of eradication as well. This may be here to stay for some time.

I've had to be in front of clients since April of 2020 for my job (B2B IT is a DOD essential pillar), and also I've had a fairly rad case of COVID (highly likely contracted from a family member) ... so my view is 1st hand on both sides there. There's a risk of driving my truck to work everyday also. I take that risk, some don't. Life is full of risks. Be smart, be reasonable, and don't live in fear.

As someone who got COVID19 , would you rather get it again or risk the vaccine?

[marurun]

So, read some stuff the other day. The Novavax vaccine is shaping up to be VERY effective, particularly against variants. It is a more traditional vaccine and was slow going because the company didn’t partner with a massive firm like Pfizer to assist with trials. And there’s something like another 11 or so MRNA vaccines still plodding along, some of which are just utterly failing to be effective. In the longer term it looks like there will be lots of choices and options for poorer countries, some of which might be much more affordable in what’s looking to be a crowded market.

[ElkinFencer10]

It does, though. For the virus to go away and stop mutating in unpredictable and, potentially, dangerous ways, we need lots of people to be vaccinated. I would like to get to a point where we don’t really worry about COVID-19 the way we don’t really worry about polio or small pox. To get there, though, more people need to get the vaccine, which, I’ll reiterate, makes you stronger, faster, smarter, and better-looking.

+1

This is why I believe the poorer countries have to be vaccinated ASAP. I also think that it should be dependent on the areas. I know, this is way too idealistic and will never happen, but an example is that the Cuban vaccine is especially effective against the Brazilian variant, so Brazil using that would be incredibly effective.

Best case scenario the countries would build on each other's vaccines to stop future variants in case they come.

Plus there are people who can't get vaccinated - folks with medical conditions like HIV, folks who are on drugs to treat other diseases that suppress their immune systems, folks who may have allergies to ingredients in the vaccines. It's our responsibility as decent and educated human beings to get vaccinated so that the herd immunity we help establish protects those who physically cannot get vaccinated. Infectious disease is not something one can fight alone.

[marurun]

Vaccination is essentially one area in which selfishness has no place.

[RCBH928]

So, read some stuff the other day. The Novavax vaccine is shaping up to be VERY effective, particularly against variants. It is a more traditional vaccine and was slow going because the company didn’t partner with a massive firm like Pfizer to assist with trials. And there’s something like another 11 or so MRNA vaccines still plodding along, some of which are just utterly failing to be effective. In the longer term it looks like there will be lots of choices and options for poorer countries, some of which might be much more affordable in what’s looking to be a crowded market.

how is one vaccine is more effective than the other? Aren't they all mRNA?

[Gucci]

From what I gathered, the Pfizer and Moderna are mRNA vaccines that require two doses.

The J&J is not nRNA and requires only one dose. Not sure exactly what kind of vaccine tech it is. That's why it was the only vaccine that had blood clotting issues. Different tech I believe.

Edit:

What is the difference between how the Johnson & Johnson vaccine works and how the Pfizer and Moderna vaccines work?
The ultimate difference is the way the instructions are delivered. The Moderna and Pfizer vaccines use mRNA technology, and the Johnson & Johnson vaccine uses the more traditional virus-based technology.

mRNA is essentially a little piece of code that the vaccine delivers to your cells. The code serves as an instruction manual for your immune system, teaching it to recognize the virus that causes COVID-19 and attack it, should it encounter the real thing.

Instead of using mRNA, the Johnson & Johnson vaccine uses a disabled adenovirus to deliver the instructions. This adenovirus is in no way related to the coronavirus. It is a completely different virus. Although it can deliver the instructions on how to defeat the coronavirus, it can’t replicate in your body and will not give you a viral infection.

Got it from here: https://www.vcuhealth.org/news/covid-19 ... -different
Hope this helps.

[marurun]

MRNA is a technology that uses messenger RNA to instruct some of the cells in your body to produce some proteins of a particular type for a short period of time, which the immune system will then attack and learn from. Some of the MRNA vaccines that are doing badly in trials did not select proteins that appear to map well to the real coronavirus. BioNTech and Moderna did choose appropriate proteins. The technology makes vaccine design a little easier, but you still have to study the original pathogen and figure out an angle of attack.

[Jagosaurus]

Sometimes I think maybe we should let people choose vaccine or not, and let natural selection just happen. They say every year many people die of the regular flue any ways.

Small pox took about 200 years of refining (look up cow pox) and a 20 years of an active campaign to eradicate.

From what I've read, this could become seasonal and basically be the next flu we fight different variants of. That changes the discussion of eradication as well. This may be here to stay for some time.

I've had to be in front of clients since April of 2020 for my job (B2B IT is a DOD essential pillar), and also I've had a fairly rad case of COVID (highly likely contracted from a family member) ... so my view is 1st hand on both sides there. There's a risk of driving my truck to work everyday also. I take that risk, some don't. Life is full of risks. Be smart, be reasonable, and don't live in fear.

As someone who got COVID19 , would you rather get it again or risk the vaccine?

Flu kills 250K to 500K ppl a year globally per CDC.

At the time I contracted it, vaccines were extremely hard to come by in my area so that's not a great discussion point around my personal timing. So I wouldn't try to use that in my input either way. That said, I'm a generally healthy guy and came out of it fine. I didn't live in fear before I had the antibodies if that answers your question. I also have to be in the field for work, so I made a choice early on to provide for my family and be around clients. I was back in office and the field full force in April of 2020.

Something a lot of people have been overlooking is the reproduction side. TMI here for non-science background folks but relevant... You know females are born with all their eggs formed? They don't develop throughout life like guys' haploid cells. A baby girl just born, already has her future kid's haploid cells already formed. Actually extremely amazing to think about if you have daugters.

So yeah... Definitely some concerns are females and future reproduction from a lot of parents right now. Might turn out fine, but potential to be telling a daughter 20 years from now she can't have kids due to a new mRNA vaccine not yet refined. I've also read some really strange things around reproductive age females I won't get into because it's not table talk lol.

Strange stuff like this happens... look up Tetracycline and Minocycline in pregnancy. Those were the latest and greatest antibiotics back then. Yet, this is why a decent amout of folks born in the 60s have permanently discolored teeth. Pregnancy and reproduction effects are the last phases of drug approval for a reason... they often take years to line out.

All of that is outside of big Pharma being opportunistic. Before everyone could even get the vaccine... they're greasing the wheels for that hypothetical booster that sure isn't free. All while watching their stock go up...

[prfsnl_gmr]

Just FYI…This is true of every new product. The test subject for long-term effects is the public, and we’re generally OK with that.

What I mean to say here is that, absent some evidence or other basis for linking a new product with a potential long-term side-effect, any position regarding the potential long-term effects of a new product is just speculation. Put another way, there is no more reason to believe that a mRNA vaccine is likely to cause fertility issues than there is reason to believe a new artificial sweetener is likely to cause you to grow bat wings. Nonetheless, people are REALLY concerned that the COVID-19 vaccine is going to harm them…in some way…eventually…we just don’t know how yet. I don’t see people boycotting products with Advantame or Stevia in the them, however, despite the fact that there are some studies that, while inconclusive, link them to cancer and nerve damage.

The point here is that, with regard to the COVID-19 vaccine, people are now suddenly very worried about potential long-term health consequences of a relatively new product, despite being almost completely unconcerned about the potential long-term health consequences associated with new drugs and food products previously. This leads me to believe that concerns regarding long-term health consequences are not the real basis for COVID-19 vaccine hesitancy:

https://www.wsj.com/articles/russian-di ... 1615129200