So far I haven't run into any significant glitches in the game. I was unable to complete a minor quest with a few Hargreaves but I think that's it. Honestly, I think a game of this scale and ambition is bound to have glitches galore. The game is massive and teaming with life. I'm not excusing Bethesda of their goofs and neglect, but I just don't see it as a deal breaker like so many here have said.
Some screenies from my game...
1920x1200 (native) Ultra, everything maxed w/ some enhanced texture mods:



What's wrong with traveling with friends:

Couple funny glitches:
Long cat IS long

I had 4 dragon carcasses in Riverwood at one time

Sticky wood

