So I guess I'll have to take it as a "by game" thing.
Right, unless hacks of some kind have been produced, but that is
doubtful for most, as they probably just built the workarounds into
the emulators themselves. There was little reason to do otherwise
before we all went reproduction and flash cart
crazyOh, I forgot about the 50/60Hz thing. Damn.
Most of the games work fine at 60Hz, just a tad faster music
and game play on some, which doesn't bother me at all.
Some run perfectly (and are timed correctly) when
running at 60Hz. Usually the only real issue to getting
the ones without software lockouts to work, is that
JPN Mega Drive games have a extra notch in them
that makes fitting them in Genesis consoles
not possible, unless you modify the port
some how, or buy a hard to find region
adapter.
So for most games, you should be OK, I would think.
Then again, I'm not a Sega Genesis expert either, I just started getting into them when the clones became available.
The Gen Mobile plays most PAL / JPN / NTSC carts perfectly, though I can't get
Duke Nukem 3D to boot, and
Daze Before Christmas won't let me get past the map screen for some reason. I think the latter is related to the fact that it has a 2 player mode, and it might be doing some funky controller port scan in the code to look for the presence of two controller ports (even Nintendo's SA-1 does that and more), at that point in the game, because otherwise it works fine :/
EDIT:
Mega Man has region lock out
Uhm, the JPN version or the PAL version?
The PAL version works perfectly on my Gen Mobile.