To get back on topic (ha! ^^;; ) these might not exactly be Super Famicom exclusives, but there were enough changes when the games got localized that they're worth getting in their original forms - Panel de Pon, Ranma 1/2 Neighborhood Combat, and Assault Suits Valken.
Panel de Pon became Tetris Attack, with MAJOR graphical changes - all the cute little anime-styled fairies became Yoshi and friends, and the final bosses became Bowser and whoever else I'm not sure of (I don't have the US version of the game... Yet!
Ranma 1/2 became Street Combat, also with major graphical changes, but this time it was worse - the anime characters became awful generic fighter characters, and I don't know what happened to the story (not sure I WANT to know either...)
Assault Suits Valken became Cybernator. This game, thankfully, didn't have much changed, except for the lack of character portraits when the characters talked, and the removal of one very pivotal final scene - the villian of the game pointing a gun at his head and shooting himself.
There might be more, but this is all I can think of at the moment!



